It's doable if Simu wanted to do it. Creatures with random names, random objects flagged as monsterbold, heavy script checks, more severe punishments, etc.
That said, I wouldn't play it unless the rewards were massive. If you got 10x exp/loot and no loot cap then maybe?
The appeal to GS today is the automation. It's a game I can play while I work. The game is way too slow and the world way too big to play manually.